Addition of rapamycin and hydroxychloroquine to metronomic chemotherapy as a second line treatment results in high salvage rates for refractory metastatic solid tumors: a pilot safety and effectiveness analysis in a small patient cohort.

Addition of rapamycin and hydroxychloroquine to metronomic chemotherapy as a second line treatment results in high salvage rates for refractory metastatic solid tumors: a pilot safety and effectiveness analysis in a small patient cohort.

Source :

• Oncotarget [ 1949-2553 ] ; 2015.

Descripteurs français

• KwdFr :
  • Administration métronomique, Adulte d'âge moyen, Autophagie (), Femelle, Humains, Hydroxychloroquine (effets indésirables), Hydroxychloroquine (usage thérapeutique), Mâle, Métastase tumorale (anatomopathologie), Métastase tumorale (traitement médicamenteux), Projets pilotes, Protocoles de polychimiothérapie antinéoplasique (effets indésirables), Protocoles de polychimiothérapie antinéoplasique (usage thérapeutique), Relation dose-effet des médicaments, Résultat thérapeutique, Sirolimus (effets indésirables), Sirolimus (usage thérapeutique), Sujet âgé, Thérapie de rattrapage, Tumeurs (anatomopathologie), Tumeurs (traitement médicamenteux).
• MESH :
  • anatomopathologie : Métastase tumorale, Tumeurs.
  • effets indésirables : Hydroxychloroquine, Protocoles de polychimiothérapie antinéoplasique, Sirolimus.
  • traitement médicamenteux : Métastase tumorale, Tumeurs.
  • usage thérapeutique : Hydroxychloroquine, Protocoles de polychimiothérapie antinéoplasique, Sirolimus.
  • Administration métronomique, Adulte d'âge moyen, Autophagie, Femelle, Humains, Mâle, Projets pilotes, Relation dose-effet des médicaments, Résultat thérapeutique, Sujet âgé, Thérapie de rattrapage.

English descriptors

• KwdEn :
  • Administration, Metronomic, Aged, Antineoplastic Combined Chemotherapy Protocols (adverse effects), Antineoplastic Combined Chemotherapy Protocols (therapeutic use), Autophagy (drug effects), Dose-Response Relationship, Drug, Female, Humans, Hydroxychloroquine (adverse effects), Hydroxychloroquine (therapeutic use), Male, Middle Aged, Neoplasm Metastasis (drug therapy), Neoplasm Metastasis (pathology), Neoplasms (drug therapy), Neoplasms (pathology), Pilot Projects, Salvage Therapy, Sirolimus (adverse effects), Sirolimus (therapeutic use), Treatment Outcome.
• MESH :
  • chemical , adverse effects : Hydroxychloroquine, Sirolimus.
  • adverse effects : Antineoplastic Combined Chemotherapy Protocols.
  • drug effects : Autophagy.
  • drug therapy : Neoplasm Metastasis, Neoplasms.
  • pathology : Neoplasm Metastasis, Neoplasms.
  • therapeutic use : Antineoplastic Combined Chemotherapy Protocols, Hydroxychloroquine, Sirolimus.
  • Administration, Metronomic, Aged, Dose-Response Relationship, Drug, Female, Humans, Male, Middle Aged, Pilot Projects, Salvage Therapy, Treatment Outcome.

Abstract

Affiliations:

• Taïwan

Links toward previous steps (curation, corpus...)

• to stream PubMed, to step Corpus: 000253
• to stream PubMed, to step Curation: 000253
• to stream PubMed, to step Checkpoint: 000260
• to stream Ncbi, to step Merge: 000292
• to stream Ncbi, to step Curation: 000292
• to stream Ncbi, to step Checkpoint: 000292
• to stream Main, to step Merge: 000F06
• to stream Main, to step Curation: 000F05

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/ChloroquineV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000F05 | SxmlIndent | more

Ou

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000F05 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    ChloroquineV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     pubmed:25944689
   |texte=   Addition of rapamycin and hydroxychloroquine to metronomic chemotherapy as a second line treatment results in high salvage rates for refractory metastatic solid tumors: a pilot safety and effectiveness analysis in a small patient cohort.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:25944689" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a ChloroquineV1 

This area was generated with Dilib version V0.6.33. Data generation: Wed Mar 25 22:43:59 2020. Site generation: Sun Jan 31 12:44:45 2021